The Innate Biologics Platform is based on engineered fusion proteins containing multiple domains. The combining of targeting/homing sequences and protein transduction domains (PTD) with the effector domains in a fusion protein is a general strategy for directing anti-inflammatory proteins to specific organs, tissues and body compartments.
Innate Biologics has pioneered a novel method to specifically target, at the molecular level, the innate intracellular inflammatory process
The innate immune system is the first line of defense against infection it has a negative effect on many bodily functions causing and exacerbating disease when ectopically activated or sustained
The Innate Biologics platform is composed of naturally-occurring, bacterial anti-inflammatory effector proteins, which have been re-engineered and re-purposed using protein transduction and tissue–specific targeting modules to create highly specific, cell and tissue-targeted anti-inflammatory activities